Noninvasively seeing a clear picture of immune cell function in vivo

Immune cell function in an individual can be monitored noninvasively in the clinic using a technique known as a PET scan. A team of researchers, led by Owen Witte, at the University of California, Los Angeles, has now determined that in mice two different PET probes used in the clinic to monitor immune cell function detect distinct immune cell populations. These data have implications for the interpretation of clinical PET scans performed with these two probes and suggest these probes could be used in the clinic to monitor the effects of drugs designed to target specific immune cell populations...

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