How Microprocessor precisely initiates miRNA production
Tuesday, June 2, 2015 - 11:30
in Biology & Nature
A scientific group from the Center for RNA Research within the Institute for Basic Science (IBS) and School of Biological Sciences in Seoul National University has reported an insightful molecular mechanism of how Microprocessor, the DROSHA-DGCR8 complex, precisely determines cleavage sites on miRNA-containing primary transcripts allowing faithful initiation of microRNA biogenesis.