Increased risk of bleeding with combined use of SSRIs and antiplatelet therapy after heart attacks

Heart attack patients taking selective serotonin reuptake inhibitors (SSRIs) in combination with antiplatelet therapy -- acetylsalicylic acid (ASA), clopidogrel or both (dual antiplatelet therapy) -- are at higher risk of bleeding than patients taking ASA alone, according to a study in CMAJ (Canadian Medical Association Journal).

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