A new approach improves prioritization of disease-associated SNPs

The more often a gene is differentially expressed, the more likely it is to contain disease-associated DNA variants. Research published today in BioMed Central's open access journal Genome Biology shows how a list of SNPs in genes that are repeatedly implicated across many publicly-available gene expression microarray experiments (so-called, 'fitSNPs'), based on differential expression rates, can be used to successfully prioritize candidate genes for further research.

Read the whole article on Physorg

More from Physorg