Yeast Knockouts Peel Back Secrets of Cell Protein Function
Monday, September 26, 2016 - 10:51
in Biology & Nature
To fill in the blanks on mitochondria, researchers at the University of Wisconsin-Madison deleted 174 genes, one by one, in yeast. They then subjected the yeast to high-intensity mass spectrometry to measure unprecedented detail on thousands of metabolic products, including proteins, intermediate chemicals called metabolites, and lipids.