Shedding Light On The Dark Zone Of Cell Division

The human body is a cross between a factory and a construction zone -- at least on the cellular level. Certain proteins act as project managers, which direct a wide variety of processes and determine the fate of the cell as a whole. One group of proteins called the WD-repeat (WDR) family helps a cell choose which of the thousands of possible gene products it should manufacture. These WDR proteins fold into a three-dimensional structure resembling a doughnut -- an unusual shape that allows WDR proteins to act as stable platforms on which large protein complexes can assemble or disassemble. read more

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