Next-Generation Sequencing Leads To Personalized Medicine Win For Teenager

Thursday, June 16, 2011 - 16:40 in Biology & Nature

Noah and Alexis Beery were diagnosed with cerebral palsy at age 2, but knowing that was only the first step on a journey to find an answer to the children's problems.  Yet a determined mother determination and the high tech world of next-generation sequencing in the Baylor Human Genome Sequencing Center were able to solve the case.Writing in Science Translational Medicine, Baylor College of Medicine researchers, along with experts in San Diego and at the University of Michigan in Ann Arbor, describe how the sequencing of the children's whole genome along with that of their older brother and their parents zeroed in on the gene that caused the children's genetic disorder, which enabled physicians to fine-tune the treatment of their disorder.read more

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