Malignancy-associated gene network regulated by RNA binding protein

Thursday, May 19, 2016 - 15:11 in Biology & Nature

The RNA binding protein IGF2BP3 is normally active in fetal tissue and undetectable in most adult tissue. But production of the protein is reactivated in many types of aggressive cancer, and it is associated with poor prognosis in both solid tumors and leukemias. New findings point toward a possible mechanism by which this protein drives metastasis.

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