Hirschsprung's disease: Research offers novel insight

Thursday, January 15, 2015 - 12:30 in Health & Medicine

Defects in the protein Sox10, a transcription factor that regulates gene expression, may play a role in the development of post-operative GI dysfunction in Hirschsprung's disease patients, according to new research. Hirschsprung's disease is a congenital disorder caused by the absence of ganglion cells in the colon, which causes problems with passing stool.

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