Rare, childhood neurodegenerative diseases linked to common problem in DNA repair

Two rare, inherited childhood neurodegenerative disorders are being studied by researchers who have identified a new, possibly common source of DNA damage that may play a role in other neurodegenerative diseases, cancer and aging. Researchers showed for the first time that an enzyme required for normal DNA functioning causes DNA damage in the developing brain. DNA is the molecule found in nearly every cell that carries the instructions needed to assemble and sustain life.

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