Biomarkers of cell death in Alzheimer's reverse course after symptom onset

Three promising biomarkers being studied to detect Alzheimer’s disease in its early stages appear to undergo a surprising shift as patients develop symptoms of dementia, researchers report. Scientists found in a recent study that the levels of markers of neuronal injury increase in the spinal fluid for a decade or more before the onset of dementia. But in a new twist, the research shows for the first time that they later reverse course, decreasing as symptoms of memory loss and mental decline appear.

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