Twenty-year quest ends as scientists pin down structure of elusive, heart-protective protein
Tuesday, July 17, 2012 - 19:00
in Biology & Nature
It is a cellular component so scarce, some scientists even doubted its existence, and many others gave up searching for its molecular structure. Now scientists have defined the protein structural composition of mitoKATP, a potassium channel in the mitochondria of the heart and other organs that is known to protect against tissue damage due to a heart attack or stroke. Importantly, the newly found channel strongly improves heart cell survival, demonstrating an essential life-saving role.