Preclinical inquiry into one mutation sheds light on addiction and a birth defect

Sunday, August 15, 2010 - 16:14 in Biology & Nature

When a certain protein is mutated or missing, symptoms of the neurodevelopmental disorder Rett syndrome arise, causing a gradual loss of brain function during early development. This fact led researchers to test a theory that the protein might also contribute to nerve-cell connection (synapse) changes in a fully formed adult mouse brain when exposed to psychostimulant use.

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