Muscle Rubs: Use For Pain Is Questionable, Review Finds

There is not enough evidence to support using gels and creams containing rubefacients for chronic and acute pain, according to a systematic review. Rubefacients cause irritation and reddening of the skin, due to increased blood flow. The review focused on formulations containing salicylates, which are widely prescribed or sold over the counter as topical treatments for sports injuries and muscle pain.

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