Inflammation, Depression And Antidepressant Response: Common Mechanisms

In findings published electronically in Molecular Psychiatry, researchers found polymorphisms in inflammation-related genes that are associated with susceptibility to major depression and antidepressant response. Two genes critical for T-cell function in the immune system have been associated with susceptibility for major depressive disorder and antidepressant treatment response: PSMB4 (proteasome beta 4 subunit) and TBX21 (T-bet).

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