How do four caged xanthones inhibit cholangiocarcinoma cell growth?

Cholangiocarcinoma (CCA) is a malignant tumour, characterised by a poor prognosis and unresponsive to conventional chemotherapeutic agents. Therefore, searching for novel and effective therapeutic agents for CCA is necessary. In previous studies, several caged xanthones from G. hanburyi have been reported to be potent antiproliferatives as well as having anticancer and anti-tumour activities and they induce apoptosis in various cancer cell lines. However, the molecular target of these compounds remains unclear...

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