Serum bile acid profiling for inflammatory bowel disease characterisation

Based on serum bank material, BA profiling was applied in IBD patients and healthy controls which showed that most but not all BA species were decreased to a different extent in CD and UC. BA decreases were highly pronounced in CD patients with surgical interventions in the gut. On the other hand, UC patients with additional liver and gallbladder diseases showed clearly increased levels of those BAs that are synthesised directly in the liver (primary BAs), or subsequently modified by intestinal bacteria (secondary BAs)...

Read the whole article on

More from