Suppressing cancer with a master control gene
Monday, February 23, 2009 - 19:35
in Biology & Nature
Starting with the tiny fruit fly and then moving into mice and humans, researchers at VIB and K. U. Leuven show that expression of the same gene suppresses cancer in all three organisms. Reciprocally, switching off the gene - called Ato in flies and ATOH1 in mammals - leads to cancer. The authors show there is a good chance that the gene can be switched on again with a drug. They report their findings in two papers in the leading online open access journal PLoS Biology...