Reduction in antibody gene rearrangement in B cells related to type 1 diabetes, lupus

More drafts usually mean a better product and so it also seems to go with the human immune system. As B cells develop, genes rearrange to allow antibodies to recognise different foreign invaders or pathogens. But sometimes antibodies are created that recognise and attack the body's own cells. These self-reactive antibodies, like early drafts of a manuscript, must be edited into versions that won't attack self...

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