DNA barcodes enable high throughput RNA and protein detection in deep tissue
Tuesday, March 11, 2025 - 12:04
in Biology & Nature
For the Liu Lab, necessity is truly the mother of invention. The researchers were examining how the 3D organization of the genome controls development and needed to image hundreds of RNA molecules in a thick tissue sample to understand where and how genes were being expressed in cells. There was just one problem: There weren't any tools that were up to the task.