Capturing transporter structure paves the way for drug development
Tuesday, May 23, 2023 - 12:13
in Health & Medicine
Scientists at St. Jude Children's Research Hospital and the University of Texas Southwestern Medical Center studied the structure and function of a transporter involved in cancer and immunity. They captured six structures of the transporter, including when it was bound to an inhibitor, providing unprecedented insight into how it works. The findings, published in Cell, have implications for drug development.