Mice need kinetochores rich in a microtubule crosslinker to achieve error-free oocyte division

Friday, July 31, 2020 - 08:30 in Biology & Nature

The error-free division of mouse oocytes—the precursors of eggs—needs kinetochores that are rich in a specific microtubule crosslinker, RIKEN researchers have discovered. This finding could explain why the division of human oocytes often gives rise to errors, and thus inform efforts to help prevent pregnancy loss and congenital disorders.

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