Toward improved wound healing: Chemical synthesis of a trefoil factor peptide
Tuesday, July 7, 2020 - 08:40
in Health & Medicine
The fascinating family of trefoil factor peptides brings hope to both research and industry to improve the treatment of chronic disorders such as Crohn's disease. For the first time, a team led by ERC awardee Markus Muttenthaler from the Faculty of Chemistry of the University of Vienna succeeded in the synthesis and folding of the peptide TFF1, a key player in mucosal protection and repair. Chemical synthesis of these gastrointestinal peptides is an important step towards a better understanding of their mode of action and therapeutic potential. The study was published in Chemical Communications.