Templating S100A9 amyloids on Aβ fibrillar surfaces revealed

Friday, June 26, 2020 - 11:40 in Biology & Nature

A research team lead by Ludmilla Morozova Roche at Umeå University, Sweden, has provided the mechanistic insight into protein co-aggregation in Alzheimer's disease. The templating mechanism of S100A9 amyloids on Aβ fibrillar surfaces during co-aggregation process was revealed by synergy of biophysical methods including charge detection mass spectrometry, microscopy, kinetic and microfluidic analyses.

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