Probing DNA damage repair
Monday, June 22, 2020 - 09:31
in Biology & Nature
Cells missing the protein HMCES are hypersensitive to DNA-damaging agents that cause a common type of DNA lesion—an "abasic" site. But the agents also generate other types of lesions associated with mutations and cell lethality, making it unclear whether HMCES responds to abasic sites in cells.