Taming CRISPR's collateral damage

Wednesday, May 27, 2020 - 07:00 in Biology & Nature

CRISPR-Cas9 can alter genes at pre-defined sites in specific ways, but it does not always act as planned. An LMU team has now developed a simple method to detect unintended "on-target" events, and shown that they often occur in human stem cells.

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