Researchers use whole living cells as 'templates' to seek for bioactive molecules
Wednesday, May 27, 2020 - 12:30
in Biology & Nature
A study performed by researchers at the Institute for Advanced Chemistry of Catalonia (IQAC) from the Spanish National Research Council (CSIC) pioneers the use of whole living cells (human lung adenocarcinoma) in dynamic combinatorial chemistry systems. This research, published in the journal Angewandte Chemie International Edition, proposes a new methodology to discover new bioactive molecules in a realistic biological medium. This methodology could help in the future to develop methods to differentiate healthy versus cancer cells, or to protect the extracellular matrix against pathogens.