Network of protein-RNA interaction guides phase separation

Friday, April 17, 2020 - 09:40 in Biology & Nature

St. Jude Children's Research Hospital investigators are studying the details of how phase separation leads to the formation of RNA granules, assemblies of protein and RNA that are not bound by a membrane. Their findings show that central nodes in a network of protein-RNA interactions drive phase separation for RNA granules, or condensates, called stress granules. The work appears today in Cell.

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