Rotavirus VP3 is a unique capping machine
Thursday, April 16, 2020 - 08:00
in Biology & Nature
After eluding researchers for more than 30 years, the VP3 protein of rotavirus has finally revealed its unique structure and function to a team led by scientists at Baylor College of Medicine. The researchers discovered that VP3 consists of four molecular modules that uniquely integrate five enzymatic activities that are necessary for capping messenger-RNA (mRNA), a process essential for the synthesis of viral proteins and for evading the host's immune response.