Zombie scanning enables the study of peptide-receptor interactions on the cell surface
Thursday, March 5, 2020 - 03:30
in Biology & Nature
In the past, biologically-active peptides—small proteins like neurotoxins and hormones that act on cell receptors to alter physiology—were purified from native sources like venoms and then panels of variants were produced in bacteria, or synthesized, to study the structural basis for receptor interaction. A new technique called zombie scanning renders these older processes obsolete.