Fungal pathogens tap human iron stores to survive immunity
Wednesday, February 19, 2020 - 09:40
in Health & Medicine
Candida species, the most prevalent opportunistic human fungal pathogens, affect severely immunocompromized individuals, and can cause severe invasive infections. The steep increase in infections by multidrug-resistant Candida glabrata pathogens has been posing serious therapeutic challenges. The prime risk factor for Candida infections is a severe immunosuppression, as often seen in the aging population, microbial super-infections, organ transplantation patients, HIV cohorts as well as neonates.