Mechanism of controlling autophagy by liquid-liquid phase separation revealed
Friday, February 14, 2020 - 11:40
in Physics & Chemistry
Under JST's Strategic Basic Research Programs, Noda Nobuo (Laboratory Head) and Fujioka Yuko (Senior Researcher) of the Institute of Microbial Chemistry, in collaboration with other researchers, discovered that a liquid-like condensate (liquid droplets) in which the Atg protein is clustered through the liquid-liquid phase separation is the structure responsible for the progression of autophagy.