A key to calcium signaling: Structure of the human IP3R type 3 in its ligand-free state
Friday, February 14, 2020 - 09:10
in Biology & Nature
IP3 receptors (IP3Rs) are calcium channels found in all animal cells. By mediating calcium ion release, IP3Rs integrate signals from different cellular pathways and metabolic states. Not surprisingly, deregulation of IP3Rs causes many diseases.