Simple single-step N-terminal modification of proteins
Thursday, February 13, 2020 - 09:20
in Physics & Chemistry
Proteins are widely used in medicine, biology and chemistry. Enhancing their inherent properties by adding functional molecules to their structures is a common and important step in many fields. For example, adding fluorescent molecules allows proteins to be traced and quantified. Many modification strategies with various advantages have been described. Osaka University researchers now report a simple N terminus-specific modification carried out under mild conditions using new reagents prepared in one step. Their findings were published online in ChemBioChem.