Researchers decode the circuitry of neuromuscular organoids

Thursday, January 16, 2020 - 11:30 in Biology & Nature

The Gouti lab from the Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC) has developed functional neuromuscular organoids (NMOs) that self-organize into spinal cord neurons and muscle tissue. Together, the two cell types form a complex neuronal network that directs muscle tissue to contract. The neuromuscular organoids, described in the journal Cell Stem Cell, represent a breakthrough for the study of human neuromuscular system development and disease.

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