New technique for in-cell distance determination
Tuesday, March 19, 2019 - 10:00
in Physics & Chemistry
In a joint paper, researchers from the University of Konstanz, Bielefeld University and ETH Zurich demonstrate for the first time that the electron paramagnetic resonance (EPR) technique RIDME (relaxation-induced dipolar modulation enhancement) can be applied to determine distances between gadolinium(III)-based spin labels in cells. In-cell distance determination by electron paramagnetic resonance (EPR) reveals essential structural information about biomacromolecules, including their conformation as well as folding and unfolding processes.