Gene transcription machinery constrains DNA movements, study suggests
Friday, March 1, 2019 - 09:10
in Biology & Nature
Researchers in Japan have discovered that the DNA inside human cells moves around less when its genes are active. The study, which will be published March 1 in the Journal of Cell Biology, suggests that RNA polymerase II (RNAPII)—the key enzyme required to produce messenger RNA molecules from active genes—restricts the movement of DNA by organizing it into a network of interconnected domains.