Controlling and visualising receptor signals in neural cells with light
Thursday, February 14, 2019 - 11:00
in Biology & Nature
Using a novel optogenetic tool, researchers have successfully controlled, reproduced and visualised serotonin receptor signals in neural cells. To this end, they modified a photosensitive membrane receptor in the eye, namely melanopsin. As a result, they were able to switch the receptor on and off using light; it also acted like a sensor indicating via fluorescence if specific signalling pathways in the cell had been activated.