The origins of asymmetry: A protein that makes you do the twist

Thursday, November 22, 2018 - 14:10 in Biology & Nature

Asymmetry plays a major role in biology at every scale: think of DNA spirals, the fact that the human heart is positioned on the left, our preference to use our left or right hand ... A team from the Institute of biology Valrose (CNRS/Inserm/Université Côte d'Azur), in collaboration with colleagues from the University of Pennsylvania, has shown how a single protein induces a spiral motion in another molecule. Through a domino effect, this causes cells, organs, and indeed the entire body to twist, triggering lateralized behaviour. This research is published in the journal Science on November 23, 2018.

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