Optical detection of picomolar concentrations of RNA using switches in plasmonic chirality
Wednesday, September 19, 2018 - 12:00
in Physics & Chemistry
Even tiny amounts of viruses can have disastrous consequences. RNA identification can reveal the type of virus present. A fast and sensitive technique based on optical detection has now been outlined in the journal Angewandte Chemie. Scientists from Germany and Finland have demonstrated the binding of an RNA target to a probe made of gold nanorods and a DNA origami structure. Chirality switches triggered by binding can be measured by circular dichroism spectroscopy.