Mutations in this molecule may have helped mammoths tolerate the cold

Monday, August 27, 2018 - 08:50 in Biology & Nature

Columbia University biomedical researchers have captured close-up views of TRPV3, a skin-cell ion channel that plays important roles in sensing temperature, itch, and pain. In humans, defects in the protein can lead to skin diseases such as atopic dermatitis (a type of eczema), vitiligo (uneven skin coloration), skin cancer, and rosacea.

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