Solving the separase–securin complex
Monday, April 24, 2017 - 05:01
in Biology & Nature
The structure of an important protein complex that regulates the metaphase-to-anaphase transition during cell cycle progression has been solved using cryo-electron microscopy (cryo-EM) at Diamond Light Source. The structural study, detailed in Nature Structural and Molecular Biology, has provided valuable insights into the inner workings of the separase–securin complex.