Dieting causes epigenetic changes during ageing

Wednesday, April 12, 2017 - 07:02 in Biology & Nature

Reduced food consumption extends the lifespan of many organisms, including primates. The biology behind how this is achieved, however, is not yet fully understood. Researchers at the Max Planck Institute for Biology of Ageing and the Cluster of Excellence for Aging Research CECAD, Cologne, Germany, as well as the Babraham Institute in Cambridge have now found that in mice, dietary restriction triggers epigenetic changes in the DNAGenes, for example, which are important for the lipid metabolism, are switched off. Dietary restriction can thus prevent the consequences of age-related changes in the so-called epigemome.

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