Molecular mechanism controlling fat accumulation elucidated

Friday, November 4, 2016 - 07:31 in Biology & Nature

Scientists in Rafal Ciosk's group at the FMI have identified a novel regulator of fat accumulation in the nematode C. elegans. An RNase, REGE-1, degrades the mRNA encoding a fat loss promoting transcription factor, ETS-4. The RNase and the transcription factor form an autoregulatory module controlling fat metabolism.

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