HybPiper: A bioinformatic pipeline for processing target-enrichment data
With the rapid rise of next-generation sequencing technologies, disparate fields from cancer research to evolutionary biology have seen a drastic shift in the way DNA sequence data is obtained. It is now possible to sequence many genes across large numbers of species in an incredibly short period of time. And the price tag keeps getting smaller and smaller. However, the deluge of sequence data obtained using these high-throughput sequencing techniques requires a substantial amount of computational input to process—a daunting task for many biologists. A recently developed bioinformatics pipeline allows researchers with limited computational skills to quickly and efficiently extract gene regions of interest from data obtained with the increasingly popular targeted sequence capture approach.