The molecular mechanism that blocks membrane receptors involved in immunological response are identified
Wednesday, October 26, 2016 - 08:31
in Biology & Nature
Nearly 70% of the drugs currently being developed target membrane receptors. Located outside the cell, these receptors play a decisive role in transmitting information to the inside of the cell. That is why in order to be able to advance in the development of more specific and more efficient drugs, the molecular mechanism that regulates the activity of these receptors needs to be deciphered. A piece of research in which the Ikerbasque researcher of the Biofisika Institute (UPV/EHU-CSIC) Xabier Contreras has participated has achieved a new advance when revealing how the receptors interact with the lipid nanodomains of the membrane. The work has been published in the prestigious journal Cell.