Gel pen offers simple strategy for improving drug development

One way to lower the cost of developing pharmaceutical drugs is by improving the predictive properties of preclinical screening. By making benchtop testing more realistic, ineffective drugs can fail faster and before they undergo expensive animal and human trials. To help tackle the issue, Alison McGuigan and her group at the University of Toronto in Canada have developed scaffold strips that can be loaded with cell populations and then rolled up to generate thick tumour sections for use in early-stage drug development.

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