Cryo-EM's renaissance: NERSC resources help illuminate human molecular machinery

Friday, July 1, 2016 - 05:51 in Biology & Nature

In a pair of breakthrough Nature papers published recently, researchers in Eva Nogales' Lab at UC Berkeley and the Lawrence Berkeley National Laboratory (Berkeley Lab) mapped two important protein functions in unprecedented detail: The role of TFIID, effectively improving our understanding of how our molecular machinery identifies the right DNA to copy; and how proteins unzip double-stranded DNA, which gives us insights in to the first-key steps in gene activation.

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