Safe and generalizable catalyst for carbonyl-olefin metathesis reaction
Wednesday, June 1, 2016 - 08:21
in Physics & Chemistry
(Phys.org)—Olefin metathesis reactions where two allyls switch substituent groups, has proved to be a useful carbon-carbon bond forming reaction for drug discovery and other industrial processes. The carbonyl-olefin metathesis reaction was discovered around the same time as the olefin metathesis reaction, but has had limited applicability due to harsh reaction conditions and stringent reactant requirements. Until now, there have been no examples of catalysts for this reaction that are generalizable.