Nanotechnology for label-free colorimetric detection of the c-myc mRNA oncogene
Thursday, March 24, 2016 - 05:30
in Health & Medicine
Given the important role in functioning as oncogenes or tumor suppressors, c-myc mRNA has emerged as a potential biomarker for cancer detection. In particular, abnormal expression of mRNAs is commonly observed at early stages of colon cancer development. Therefore, sensitive detection of c-myc mRNA has become a promising approach to achieving early clinical diagnosis of cancer and paves the way for precision medicine. Recently, a China-U.S. collaborative research team reported a label-free colorimetric protocol based on peptide nucleic acid/silver nanoparticles (PNA/AgNPs) for specific detection of c-myc mRNA biomarkers.